HPE ProLiant DL380 Gen11 Xeon Gold 5416S Rack Server

HPE ProLiant DL380 Gen11 Xeon Gold 5416S Rack Server, 32GB RAM, MR408i‑o RAID, 8x SFF (P52561‑421)

The HPE ProLiant DL380 Gen11 Xeon Gold 5416S Rack Server (P52561‑421) is a powerful, enterprise‑class mid-range rack server designed for virtualization, databases, application hosting, and business‑critical workloads. Built on HPE’s flagship 2U ProLiant platform, this configuration combines the performance of Intel Xeon Gold 5416S, reliable ECC memory, and flexible storage in a highly efficient form factor.

This model includes one Intel Xeon Gold 5416S processor, 32 GB (1×32 GB) dual rank memory, an HPE MR408i‑o Gen11 x8 Lanes 4GB Cache OCP SPDM Storage Controller, drive bays for up to 8 small form factor (SFF) drives, four standard fans, and one HPE 1000W Flex Slot Titanium Hot Plug Power Supply Kit. It is backed by a 3/3/3 warranty (3 years parts, 3 years labour, 3 years onsite), offering predictable lifecycle costs and dependable uptime.

As your infrastructure grows, this HPE ProLiant DL380 Gen11 Xeon Gold 5416S Rack Server can be combined with additional rack and tower systems from the broader servers lineup to build a scalable hybrid or on‑premise cloud environment.

Detailed Specification Table

Common Suitable Users

The HPE ProLiant DL380 Gen11 Xeon Gold 5416S Rack Server is ideal for:

• Medium & Large Enterprises
  Running multi‑tier applications, ERP/CRM, collaboration platforms, and mixed workloads on a powerful mid‑range rack server.
• Data Centres & Co‑Location Facilities
  Deploying compute and storage nodes that balance performance, density, and energy efficiency.
• Managed Service Providers (MSPs)
  Hosting customer VMs, databases, and applications in multi‑tenant or dedicated environments.
• Growing SMBs with High Demands
  Standardizing on a robust 2U platform for virtualized workloads, databases, and critical business services.
• Campus & Branch Aggregation
  Acting as a central server for campus‑wide or regional services, including authentication, file/print, and business apps.
• Backup, DR & Secondary Roles
  Serving as a high‑performance backup or disaster recovery target alongside primary production servers.

Key Pros of HPE ProLiant DL380 Gen11 Xeon Gold 5416S Rack Server, P52561‑421

• Enterprise‑Class Xeon Gold Performance
  Intel Xeon Gold 5416S delivers higher performance and scalability than entry‑level CPUs, ideal for heavier workloads.
• Flexible, Proven 2U DL380 Platform
  Widely adopted, highly configurable ProLiant chassis suitable for a broad range of data‑centre roles.
• ECC RDIMM Memory with Expansion Headroom
  32 GB dual rank as a reliable starting point, with extensive room for scaling memory capacity over time.
• Powerful MR408i‑o Gen11 Storage Controller
  4GB cache and x8 lanes provide strong RAID performance and data resilience for the 8‑bay SFF backplane.
• Eight SFF Drive Bays
  Ideal for mixing SSDs and HDDs, building performance tiers or all‑flash layouts for databases and VMs.
• High‑Efficiency 1000W Titanium PSU
  Titanium Flex Slot PSU maximizes power efficiency and supports hot‑plug replacement to reduce downtime.
• Robust Cooling with Four Standard Fans
  Designed for continuous 24/7 data‑centre operation, maintaining stable thermals under load.
• Integrated HPE iLO Management
  Enterprise‑grade remote management simplifies monitoring, firmware updates, and troubleshooting from anywhere.
• 3/3/3 Enterprise Warranty
  Three years of onsite parts and labour reduce risk and improve planning for lifecycle and maintenance.

Market Price Variation Table

The price ranges below are approximate and for content guidance. Actual pricing depends on RAM and storage configuration, options (extra NICs, GPUs), support upgrades, and FX rates.

Pricing can fluctuate with promotions, component availability, and whether deployment or migration services are bundled.

Summary & Conclusion

The HPE ProLiant DL380 Gen11 Xeon Gold 5416S Rack Server, 32GB dual rank memory, HPE MR408i‑o Gen11 4GB cache storage controller, support for 8 SFF drives, four standard fans, and a 1000W Titanium Flex Slot hot‑plug PSU (P52561‑421) is a robust, future‑ready mid‑range rack server for demanding business workloads.

It offers a powerful combination of compute performance, storage flexibility, energy efficiency, and enterprise‑grade management, making it an excellent choice for virtualization clusters, databases, application hosting, and hybrid IT roles. Backed by a comprehensive 3/3/3 warranty, this configuration can serve as the core of your server room or data centre, with the option to scale out alongside other HPE ProLiant DL380 Gen11 Xeon Gold 5416S Rack Server as your workload and capacity requirements grow.